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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
01/11/2018 |
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Actualizado : |
07/11/2018 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
ZARANTONELLI, L.; SUANES, A.; MENY, P.; BURONI, F.; SALVARREY,X.; BRIANO , C.; ASHFIELD, N.; SILVEIRA, C.S.; DUTRA, F.; EASTON, C.; FRAGA, M.; GIANNITTI, F.; HAMOND, C.; MACÍAS-RIOSECO, M.; MENÉNDEZ, C.; MORTOLA, A.; PICARDEAU, M. |
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Afiliación : |
LETICIA ZARANTONELLI, Laboratorio de Microbiología Molecular y Estructural, Institut Pasteur de Montevideo, Uruguay.; Unidad Mixta UMPI, Institut Pasteur de Montevideo; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.; ALEJANDRA SUANES, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; PAULINA MENY, Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Uruguay.; FLORENCIA BURONI, División Laboratorios Veterinarios "Miguel C. Rubino" Laboratorio Regional Noroeste, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; XIMENA SALVARREY, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino". Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay .; CAROLINA BRIANO, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay .; NATALIA ASHFIELD4, Departamento de Bacteriología y Virologí, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Uruguay.; CAROLINE DA SILVA SILVEIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO DUTRA, División Laboratorios Veterinarios "Miguel C. Rubino". Laboratorio Regional Este, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; CRISTINA EASTON, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; MARTIN FRAGA COTELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CAMILA HAMOND, Unidad Mixta UMPI, Institut Pasteur de Montevideo ; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MELISSA MACÍAS RIOSECO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CLARA MENÉNDEZ, Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Uruguay.; ALBERTO MORTOLA, Departamento de Bacteriología, División Laboratorios Veterinarios "Miguel C. Rubino" Sede Central, Ministerio de Ganadería, Agricultura y Pesca, Uruguay.; MATHIEU PICARDEAU, Institut Pasteur de Montevideo, Uruguay. / Institut Pasteur, France. |
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Título : |
Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
PLoS Neglected Tropical Diseases, September 2018, vol. 12, Issue 9, Article number e0006694. OPEN ACCESS. |
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DOI : |
10.1371/journal.pntd.0006694 |
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Idioma : |
Inglés |
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Notas : |
Article History: Received: February 8, 2018; Accepted: July 16, 2018; Published: September 13, 2018. |
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Contenido : |
Abstract:
Leptospirosis is a neglected zoonosis with worldwide distribution. The causative agents are spirochete bacteria of the Leptospira genus, displaying huge diversity of serovars, the identity of which is critical for effective diagnosis and vaccination purposes. Among many other mammalian species, Leptospira infects cattle, eliciting acute signs in calves, and chronic disease in adult animals often leading to abortions. In South America, and including in Uruguay, beef and dairy export are leading sources of national income. Despite the importance of bovine health, food safety, and bovine-related dissemination of leptospirosis to humans, extremely limited information is available as to the identity of Leptospira species and serovars infecting cattle in Uruguay and the South American subcontinent. Here we report a multicentric 3-year study resulting in the isolation and detailed characterization of 40 strains of Leptospira spp. obtained from infected cattle. Combined serologic and molecular typing identified these isolates as L. interrogans serogroup Pomona serovar Kennewicki (20 strains), L. interrogans serogroup Canicola serovar Canicola (1 strain), L. borgpetersenii serogroup Sejroe serovar Hardjo (10 strains) and L. noguchii (9 strains). The latter showed remarkable phenotypic and genetic variability, belonging to 6 distinct serogroups, including 3 that did not react with a large panel of reference serogrouping antisera. Approximately 20% of cattle sampled in the field were found to be shedding pathogenic Leptospira in their urine, uncovering a threat for public health that is being largely neglected. The two L. interrogans serovars that we isolated from cattle displayed identical genetic signatures to those of human isolates that had previously been obtained from leptospirosis patients. This report of local Leptospira strains shall improve diagnostic tools and the understanding of leptospirosis epidemiology in South America. These strains could also be used as new components within bacterin vaccines to protect against the pathogenic Leptospira strains that are actually circulating, a direct measure to reduce the risk of human leptospirosis.
© 2018 Zarantonelli et al. http://creativecommons.org/licenses/by/4.0/. MenosAbstract:
Leptospirosis is a neglected zoonosis with worldwide distribution. The causative agents are spirochete bacteria of the Leptospira genus, displaying huge diversity of serovars, the identity of which is critical for effective diagnosis and vaccination purposes. Among many other mammalian species, Leptospira infects cattle, eliciting acute signs in calves, and chronic disease in adult animals often leading to abortions. In South America, and including in Uruguay, beef and dairy export are leading sources of national income. Despite the importance of bovine health, food safety, and bovine-related dissemination of leptospirosis to humans, extremely limited information is available as to the identity of Leptospira species and serovars infecting cattle in Uruguay and the South American subcontinent. Here we report a multicentric 3-year study resulting in the isolation and detailed characterization of 40 strains of Leptospira spp. obtained from infected cattle. Combined serologic and molecular typing identified these isolates as L. interrogans serogroup Pomona serovar Kennewicki (20 strains), L. interrogans serogroup Canicola serovar Canicola (1 strain), L. borgpetersenii serogroup Sejroe serovar Hardjo (10 strains) and L. noguchii (9 strains). The latter showed remarkable phenotypic and genetic variability, belonging to 6 distinct serogroups, including 3 that did not react with a large panel of reference serogrouping antisera. Approximately 20% of cattle sampled in the fi... Presentar Todo |
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Palabras claves : |
SALUD ANIMAL. |
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Thesagro : |
LEPTOSPIRA; LEPTOSPIROSIS. |
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Asunto categoría : |
-- |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/11772/1/Zarantonelli-2018-Isolation-of-pathogenic-leptospira-1.pdf
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Marc : |
LEADER 03472naa a2200373 a 4500
001 1059268
005 2018-11-07
008 2018 bl uuuu u00u1 u #d
024 7 $a10.1371/journal.pntd.0006694$2DOI
100 1 $aZARANTONELLI, L.
245 $aIsolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis.
260 $c2018
500 $aArticle History: Received: February 8, 2018; Accepted: July 16, 2018; Published: September 13, 2018.
520 $aAbstract: Leptospirosis is a neglected zoonosis with worldwide distribution. The causative agents are spirochete bacteria of the Leptospira genus, displaying huge diversity of serovars, the identity of which is critical for effective diagnosis and vaccination purposes. Among many other mammalian species, Leptospira infects cattle, eliciting acute signs in calves, and chronic disease in adult animals often leading to abortions. In South America, and including in Uruguay, beef and dairy export are leading sources of national income. Despite the importance of bovine health, food safety, and bovine-related dissemination of leptospirosis to humans, extremely limited information is available as to the identity of Leptospira species and serovars infecting cattle in Uruguay and the South American subcontinent. Here we report a multicentric 3-year study resulting in the isolation and detailed characterization of 40 strains of Leptospira spp. obtained from infected cattle. Combined serologic and molecular typing identified these isolates as L. interrogans serogroup Pomona serovar Kennewicki (20 strains), L. interrogans serogroup Canicola serovar Canicola (1 strain), L. borgpetersenii serogroup Sejroe serovar Hardjo (10 strains) and L. noguchii (9 strains). The latter showed remarkable phenotypic and genetic variability, belonging to 6 distinct serogroups, including 3 that did not react with a large panel of reference serogrouping antisera. Approximately 20% of cattle sampled in the field were found to be shedding pathogenic Leptospira in their urine, uncovering a threat for public health that is being largely neglected. The two L. interrogans serovars that we isolated from cattle displayed identical genetic signatures to those of human isolates that had previously been obtained from leptospirosis patients. This report of local Leptospira strains shall improve diagnostic tools and the understanding of leptospirosis epidemiology in South America. These strains could also be used as new components within bacterin vaccines to protect against the pathogenic Leptospira strains that are actually circulating, a direct measure to reduce the risk of human leptospirosis. © 2018 Zarantonelli et al. http://creativecommons.org/licenses/by/4.0/.
650 $aLEPTOSPIRA
650 $aLEPTOSPIROSIS
653 $aSALUD ANIMAL
700 1 $aSUANES, A.
700 1 $aMENY, P.
700 1 $aBURONI, F.
700 1 $aSALVARREY,X.
700 1 $aBRIANO , C.
700 1 $aASHFIELD, N.
700 1 $aSILVEIRA, C.S.
700 1 $aDUTRA, F.
700 1 $aEASTON, C.
700 1 $aFRAGA, M.
700 1 $aGIANNITTI, F.
700 1 $aHAMOND, C.
700 1 $aMACÍAS-RIOSECO, M.
700 1 $aMENÉNDEZ, C.
700 1 $aMORTOLA, A.
700 1 $aPICARDEAU, M.
773 $tPLoS Neglected Tropical Diseases, September 2018, vol. 12, Issue 9, Article number e0006694. OPEN ACCESS.
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Registro original : |
INIA La Estanzuela (LE) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas; INIA Treinta y Tres. |
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Fecha actual : |
12/03/2019 |
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Actualizado : |
12/03/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
QUERO, G.; GUTIÉRREZ, L.; MONTEVERDE, E.; BLANCO, P.H.; PÉREZ DE VIDA, F.; ROSAS, J.E.; FERNANDEZ, S.; GARAYCOCHEA, S.; MC COUCH, S.; BERBERIAN, N.; SIMONDI, S.; BONNECARRERE, V. |
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Afiliación : |
GASTÓN QUERO CORRALLO, Universidad de la República (UdelaR)/ Facultad de Agronomía; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; LUCÍA GUTIÉRREZ, Dep. of Agronomy, Univ. of Wisconsin-Madison, United States.; Universidad de la República (UdelaR)/ Facultad de Agronomía; ELIANA MONTEVERDE, Dep. of Plant Breeding and Genetics, Cornell Univ., United States; PEDRO HORACIO BLANCO BARRAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO BLAS PEREZ DE VIDA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JUAN EDUARDO ROSAS CAISSIOLS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SCHUBERT DANIEL FERNANDEZ REGGIARDO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SILVIA RAQUEL GARAYCOCHEA SOLSONA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SUSAN MCCOUCH, Dep. of Plant Breeding and Genetics, Cornell Univ., United States; NATALIA BERBERIAN, Universidad de la República (UdelaR)/ Facultad de Agronomía; SEBASTIÁN SIMONDI, College of Natural and Exact Sciences, Univ. Nacional de Cuyo, Argentina; MARIA VICTORIA BONNECARRERE MARTINEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Genome-wide association study using historical breeding populations discovers genomic regions involved in high-quality rice. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
Plant Genome, 2018, Volume 11, Article number 170076. Open Access. |
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ISSN : |
1940-3372 |
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DOI : |
10.3835/plantgenome2017.08.0076 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: Aug 25, 2017 // Accepted: Apr 09, 2018 // Published: July 12, 2018.
Permissions: This is an open access article under the CC BY-NC-ND license. Proper attribution is required for reuse. No permissions are needed for reuse unless it is derivative or for commercial purposes. |
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Contenido : |
Abstract.
Rice (Oryza sativa L.) is one of the most important staple food crops in the world; however, there has recently been a shift in consumer demand for higher grain quality. Therefore, understanding the genetic architecture of grain quality has become a key objective of rice breeding programs. Genomewide association studies (GWAS) using large diversity panels have successfully identified genomic regions associated with complex traits in diverse crop species. Our main objective was to identify genomic regions associated with grain quality and to identify and characterize favorable haplotypes for selection. We used two locally adapted rice breeding populations and historical phenotypic data for three rice quality traits: yield after milling, percentage of head rice recovery, and percentage of chalky grain. We detected 22 putative quantitative trait loci (QTL) in the same genomic regions as starch synthesis, starch metabolism, and cell wall synthesis-related genes are found. Additionally, we found a genomic region on chromosome 6 in the tropical japonica population that was associated with all quality traits and we identified favorable haplotypes. Furthermorethis region is linked to the OsBEI gene that codes for a starch branching enzyme I, which is implicated in starch granule formation. In tropical japonica, we also found two putative QTL linked to OsBEII, OsDEP1, and OsDEP2. Our study provides an insight into the genetic basis of rice grain chalkiness, yield after milling, and head rice, identifying favorable haplotypes and molecular markers for selection in breeding programs.
© 2018 Crop Science Society of America MenosAbstract.
Rice (Oryza sativa L.) is one of the most important staple food crops in the world; however, there has recently been a shift in consumer demand for higher grain quality. Therefore, understanding the genetic architecture of grain quality has become a key objective of rice breeding programs. Genomewide association studies (GWAS) using large diversity panels have successfully identified genomic regions associated with complex traits in diverse crop species. Our main objective was to identify genomic regions associated with grain quality and to identify and characterize favorable haplotypes for selection. We used two locally adapted rice breeding populations and historical phenotypic data for three rice quality traits: yield after milling, percentage of head rice recovery, and percentage of chalky grain. We detected 22 putative quantitative trait loci (QTL) in the same genomic regions as starch synthesis, starch metabolism, and cell wall synthesis-related genes are found. Additionally, we found a genomic region on chromosome 6 in the tropical japonica population that was associated with all quality traits and we identified favorable haplotypes. Furthermorethis region is linked to the OsBEI gene that codes for a starch branching enzyme I, which is implicated in starch granule formation. In tropical japonica, we also found two putative QTL linked to OsBEII, OsDEP1, and OsDEP2. Our study provides an insight into the genetic basis of rice grain chalkiness, yield after mil... Presentar Todo |
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Palabras claves : |
FOOD GRAIN; GENETIC SELECTION; GENETIC VARIATION; GENETICS; MILLED RICE; PLANT BREEDING. |
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Thesagro : |
ORYZA SATIVA; RICE. |
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Asunto categoría : |
F01 Cultivo |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/12507/1/tpg-11-3-170076.pdf
https://dl.sciencesocieties.org/publications/tpg/abstracts/11/3/170076
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Marc : |
LEADER 03044naa a2200385 a 4500
001 1059613
005 2019-03-12
008 2018 bl uuuu u00u1 u #d
022 $a1940-3372
024 7 $a10.3835/plantgenome2017.08.0076$2DOI
100 1 $aQUERO, G.
245 $aGenome-wide association study using historical breeding populations discovers genomic regions involved in high-quality rice.$h[electronic resource]
260 $c2018
500 $aArticle history: Received: Aug 25, 2017 // Accepted: Apr 09, 2018 // Published: July 12, 2018. Permissions: This is an open access article under the CC BY-NC-ND license. Proper attribution is required for reuse. No permissions are needed for reuse unless it is derivative or for commercial purposes.
520 $aAbstract. Rice (Oryza sativa L.) is one of the most important staple food crops in the world; however, there has recently been a shift in consumer demand for higher grain quality. Therefore, understanding the genetic architecture of grain quality has become a key objective of rice breeding programs. Genomewide association studies (GWAS) using large diversity panels have successfully identified genomic regions associated with complex traits in diverse crop species. Our main objective was to identify genomic regions associated with grain quality and to identify and characterize favorable haplotypes for selection. We used two locally adapted rice breeding populations and historical phenotypic data for three rice quality traits: yield after milling, percentage of head rice recovery, and percentage of chalky grain. We detected 22 putative quantitative trait loci (QTL) in the same genomic regions as starch synthesis, starch metabolism, and cell wall synthesis-related genes are found. Additionally, we found a genomic region on chromosome 6 in the tropical japonica population that was associated with all quality traits and we identified favorable haplotypes. Furthermorethis region is linked to the OsBEI gene that codes for a starch branching enzyme I, which is implicated in starch granule formation. In tropical japonica, we also found two putative QTL linked to OsBEII, OsDEP1, and OsDEP2. Our study provides an insight into the genetic basis of rice grain chalkiness, yield after milling, and head rice, identifying favorable haplotypes and molecular markers for selection in breeding programs. © 2018 Crop Science Society of America
650 $aORYZA SATIVA
650 $aRICE
653 $aFOOD GRAIN
653 $aGENETIC SELECTION
653 $aGENETIC VARIATION
653 $aGENETICS
653 $aMILLED RICE
653 $aPLANT BREEDING
700 1 $aGUTIÉRREZ, L.
700 1 $aMONTEVERDE, E.
700 1 $aBLANCO, P.H.
700 1 $aPÉREZ DE VIDA, F.
700 1 $aROSAS, J.E.
700 1 $aFERNANDEZ, S.
700 1 $aGARAYCOCHEA, S.
700 1 $aMC COUCH, S.
700 1 $aBERBERIAN, N.
700 1 $aSIMONDI, S.
700 1 $aBONNECARRERE, V.
773 $tPlant Genome, 2018, Volume 11, Article number 170076. Open Access.
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